How do you approach a neighbour with screaming teenagers?

My next door neighbour has two children, both around 11-15. Every single day, without fail, there are screaming matches between 15:30 and 17:30. It also happens 3-4 times a week at 23:00 and later. A few times I’ve been on conference calls and I’ve had to mute myself due to it being a distraction. The son is the culprit, he screams and threatens his sister and then she retaliates. Sometimes the mum joins in the shouting too, not even trying to sort it but screaming at them for screaming. I completely understand that there may be more going on, but I don’t know how to approach it to my neighbour. We don’t speak much, we’ve only had a couple of conversations. I’m not a moany person, people have lives and I don’t expect pure silence at all times… I’m more concerned for the well-being of the family as a whole. So, do I bring it up to my neighbour? If so, how? Do I ignore it and hope it goes away? Or option c… taking suggestions!