What is the best board/card game to get two singleton talking?

Are they already established board gamers? Some of the suggestions here just don't work if they are not familiar with modern games. For my pick, Just One. It is my gateway game at every event I have ran, and a great ice breaker. Give a clue to help someone guess a word, but if anyone puts the same clue the get deleted before the guesser sees them. Hitster is great too, guess the year for music, people very quickly start reminiscing about the songs and open up. Ignore the rules, just make a big timeline as a group. Trio is a great little card game about making sets and stealing cards from other people. Roll For It, if you can find a copy, is a good quick push your luck dice game. You want quick, easy to learn games to get people talking. Don't go in with anything with an actual board is my rule, people spend too much time in their own heads figuring out rules and strategies. You also don't want Warewolf or Hitler because people are not going to talk casually for fear of being 'accused' in game.