Why is cylinder deactivation/variable displacement generally considered so bad for long-term reliability? What are examples of cars/engines that use it with minimal issues?

Posted by KSoMA@reddit | cars | View on Reddit | 137 comments

Asking after discussion with a friend. Many cases of modern reliability issues are blamed on variable displacement, such as the 6.4L HEMI. Is this actually a widespread issue, or is it a case of something that hasn't actually become a big deal, like arguably auto start-stop?