Hypotheticals:
George has a history of entering a diabetic comas due to poor management of his diabetes. He was involved in a single car collision 14 months ago as a result of this.
He passed out while in a grocery store 30 days ago as a result of this.
He presents to you today in overall good health, reasonable blood sugar levels, and a good demeanor.

Do you issue him a medical? For how long?

Lindsey has a history of high blood pressure and had a minor heart attack 8 months prior. She presents to you with minor atrial fibrillation, which on its own would not be cause for concern. She states that only happens when she costumes caffeine. She reports that in the last 12 hours, she only drank about half of an 8oz RedBull which was while driving to your office. She reports that she usually drinks 3-4 RedBulls per day.

Do you issue her a medical? For how long?

Jeff presents to you with no medical ailments, but reporting a history of "managed drug use" in order to stay alert for 24+ hours at a time. Jeff reports that he has been "away from work" for the last 60 days, and provides a clean urine sample today.

Do you issue him a medical? For how long?

Stacy reports having an average of 2 broken bones per year for the last 10 years. She reports no dangerous hobbies, and states that the broken bones occurred "during normal day-to-day activities." She states that because it's so mundane, she doesn't remember how each one occurred, but the last time she broke a bone, it was because an approximately 2 pound lamp fell off the desk, and she caught it awkwardly, breaking 2 fingers.
She presents to you with no broken bones, and in generally good health.

Do you issue her a medical? For how long?

Frank reports a history of roughly monthly seizures. He states they started when he was about 15, and have been roughly stable, averaging 1 per month. He states that he, "Can feel it when it is about to happen." He reports that the seizures have never caused a collision.
He is otherwise in good health, and does not experience a seizure in your presence.

Do you issue him a medical? For how long?

Barbara presents as morbidly obese, with blood pressure managed by medication. She reports feeling tired every day, and waking up in the middle of the night gasping for air. She states that these feelings do not impact her ability to function day-to-day, and she knows to stop driving when tired.

Do you issue her a medical? For how long?